Table: q1_q4_2022_prescription_drug_wac_increases_5_year_history , manufacturer_name like I*

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manufacturer_name	ndc_number	effective_date	history_effective_date	wac_increase_amount	wac_amount
Incyte Corporation	50881000560	2022-07-01 00:00:00	2017-12-01 00:00:00	693	12240
Incyte Corporation	50881000560	2022-07-01 00:00:00	2018-08-31 00:00:00	367	12607
Incyte Corporation	50881000560	2022-07-01 00:00:00	2018-12-28 00:00:00	504	13111
Incyte Corporation	50881000560	2022-07-01 00:00:00	2019-10-01 00:00:00	393	13504
Incyte Corporation	50881000560	2022-07-01 00:00:00	2020-07-13 00:00:00	270	13774
Incyte Corporation	50881000560	2022-07-01 00:00:00	2020-11-02 00:00:00	413	14187
Incyte Corporation	50881000560	2022-07-01 00:00:00	2021-04-05 00:00:00	567	14754
Incyte Corporation	50881000560	2022-07-01 00:00:00	2021-10-07 00:00:00	369	15123
Incyte Corporation	50881000560	2022-07-01 00:00:00	2022-01-07 00:00:00	454	15577
Incyte Corporation	50881000560	2022-07-01 00:00:00	2022-07-01 00:00:00	623	16200
Incyte Corporation	50881001060	2022-07-01 00:00:00	2017-12-01 00:00:00	693	12240
Incyte Corporation	50881001060	2022-07-01 00:00:00	2018-08-31 00:00:00	367	12607
Incyte Corporation	50881001060	2022-07-01 00:00:00	2018-12-28 00:00:00	504	13111
Incyte Corporation	50881001060	2022-07-01 00:00:00	2019-10-01 00:00:00	393	13504
Incyte Corporation	50881001060	2022-07-01 00:00:00	2020-07-13 00:00:00	270	13774
Incyte Corporation	50881001060	2022-07-01 00:00:00	2020-11-02 00:00:00	413	14187
Incyte Corporation	50881001060	2022-07-01 00:00:00	2021-04-05 00:00:00	567	14754
Incyte Corporation	50881001060	2022-07-01 00:00:00	2021-10-07 00:00:00	369	15123
Incyte Corporation	50881001060	2022-07-01 00:00:00	2022-01-07 00:00:00	454	15577
Incyte Corporation	50881001060	2022-07-01 00:00:00	2022-07-01 00:00:00	623	16200
Incyte Corporation	50881001560	2022-07-01 00:00:00	2017-12-01 00:00:00	693	12240
Incyte Corporation	50881001560	2022-07-01 00:00:00	2018-08-31 00:00:00	367	12607
Incyte Corporation	50881001560	2022-07-01 00:00:00	2018-12-28 00:00:00	504	13111
Incyte Corporation	50881001560	2022-07-01 00:00:00	2019-10-01 00:00:00	393	13504
Incyte Corporation	50881001560	2022-07-01 00:00:00	2020-07-13 00:00:00	270	13774
Incyte Corporation	50881001560	2022-07-01 00:00:00	2020-11-02 00:00:00	413	14187
Incyte Corporation	50881001560	2022-07-01 00:00:00	2021-04-05 00:00:00	567	14754
Incyte Corporation	50881001560	2022-07-01 00:00:00	2021-10-07 00:00:00	369	15123
Incyte Corporation	50881001560	2022-07-01 00:00:00	2022-01-07 00:00:00	454	15577
Incyte Corporation	50881001560	2022-07-01 00:00:00	2022-07-01 00:00:00	623	16200
Incyte Corporation	50881002060	2022-07-01 00:00:00	2017-12-01 00:00:00	693	12240
Incyte Corporation	50881002060	2022-07-01 00:00:00	2018-08-31 00:00:00	367	12607
Incyte Corporation	50881002060	2022-07-01 00:00:00	2018-12-28 00:00:00	504	13111
Incyte Corporation	50881002060	2022-07-01 00:00:00	2019-10-01 00:00:00	393	13504
Incyte Corporation	50881002060	2022-07-01 00:00:00	2020-07-13 00:00:00	270	13774
Incyte Corporation	50881002060	2022-07-01 00:00:00	2020-11-02 00:00:00	413	14187
Incyte Corporation	50881002060	2022-07-01 00:00:00	2021-04-05 00:00:00	567	14754
Incyte Corporation	50881002060	2022-07-01 00:00:00	2021-10-07 00:00:00	369	15123
Incyte Corporation	50881002060	2022-07-01 00:00:00	2022-01-07 00:00:00	454	15577
Incyte Corporation	50881002060	2022-07-01 00:00:00	2022-07-01 00:00:00	623	16200
Incyte Corporation	50881002560	2022-07-01 00:00:00	2017-12-01 00:00:00	693	12240
Incyte Corporation	50881002560	2022-07-01 00:00:00	2018-08-31 00:00:00	367	12607
Incyte Corporation	50881002560	2022-07-01 00:00:00	2018-12-28 00:00:00	504	13111
Incyte Corporation	50881002560	2022-07-01 00:00:00	2019-10-01 00:00:00	393	13504
Incyte Corporation	50881002560	2022-07-01 00:00:00	2020-07-13 00:00:00	270	13774
Incyte Corporation	50881002560	2022-07-01 00:00:00	2020-11-02 00:00:00	413	14187
Incyte Corporation	50881002560	2022-07-01 00:00:00	2021-04-05 00:00:00	567	14754
Incyte Corporation	50881002560	2022-07-01 00:00:00	2021-10-07 00:00:00	369	15123
Incyte Corporation	50881002560	2022-07-01 00:00:00	2022-01-07 00:00:00	454	15577
Incyte Corporation	50881002560	2022-07-01 00:00:00	2022-07-01 00:00:00	623	16200
Ingenus Pharmaceuticals, LLC	50742051330	2022-04-11 00:00:00	2018-08-01 00:00:00	128.76	391.53
Ingenus Pharmaceuticals, LLC	50742051330	2022-04-11 00:00:00	2019-08-01 00:00:00	129.2	520.73
Ingenus Pharmaceuticals, LLC	50742051330	2022-04-11 00:00:00	2022-04-11 00:00:00	182.26	702.99
Ingenus Pharmaceuticals, LLC	50742051430	2022-04-11 00:00:00	2018-08-01 00:00:00	138.53	421.25
Ingenus Pharmaceuticals, LLC	50742051430	2022-04-11 00:00:00	2019-08-01 00:00:00	139.01	560.26
Ingenus Pharmaceuticals, LLC	50742051430	2022-04-11 00:00:00	2022-04-11 00:00:00	196.09	756.35
Ingenus Pharmaceuticals, LLC	50742051530	2022-04-11 00:00:00	2018-08-01 00:00:00	155.29	472.21
Ingenus Pharmaceuticals, LLC	50742051530	2022-04-11 00:00:00	2019-08-01 00:00:00	155.83	628.04
Ingenus Pharmaceuticals, LLC	50742051530	2022-04-11 00:00:00	2020-05-01 00:00:00	314.02	942.06
Ingenus Pharmaceuticals, LLC	50742051530	2022-04-11 00:00:00	2021-02-15 00:00:00	235.52	1177.52
Ingenus Pharmaceuticals, LLC	50742051530	2022-04-11 00:00:00	2022-04-11 00:00:00	412.15	1589.73
Ingenus Pharmaceuticals, LLC	50742051630	2022-04-11 00:00:00	2018-08-01 00:00:00	155.92	472.21
Ingenus Pharmaceuticals, LLC	50742051630	2022-04-11 00:00:00	2019-08-01 00:00:00	155.83	628.04
Ingenus Pharmaceuticals, LLC	50742051630	2022-04-11 00:00:00	2022-04-11 00:00:00	219.81	847.85
Ingenus Pharmaceuticals, LLC	50742051730	2022-04-11 00:00:00	2018-08-01 00:00:00	168.42	512.13
Ingenus Pharmaceuticals, LLC	50742051730	2022-04-11 00:00:00	2019-08-01 00:00:00	169	681.13
Ingenus Pharmaceuticals, LLC	50742051730	2022-04-11 00:00:00	2022-04-11 00:00:00	238.4	919.53
Ingenus Pharmaceuticals, LLC	50742051830	2022-04-11 00:00:00	2018-08-01 00:00:00	168.42	512.13
Ingenus Pharmaceuticals, LLC	50742051830	2022-04-11 00:00:00	2019-08-01 00:00:00	169	681.13
Ingenus Pharmaceuticals, LLC	50742051830	2022-04-11 00:00:00	2020-05-01 00:00:00	340.57	1021.7
Ingenus Pharmaceuticals, LLC	50742051830	2022-04-11 00:00:00	2021-02-15 00:00:00	255.43	1277.13
Ingenus Pharmaceuticals, LLC	50742051830	2022-04-11 00:00:00	2022-04-11 00:00:00	446.99	1724.12
Insmed Incorporated	71558059028	2022-01-01 00:00:00	2019-07-01 00:00:00	813	10977
Insmed Incorporated	71558059028	2022-01-01 00:00:00	2020-01-01 00:00:00	648.99	11625.99
Insmed Incorporated	71558059028	2022-01-01 00:00:00	2021-01-01 00:00:00	755.69	12381.68
Insmed Incorporated	71558059028	2022-01-01 00:00:00	2022-01-01 00:00:00	990.53	13372.21
Intercept Pharmaceuticals, Inc.	69516000530	2022-01-20 00:00:00	2017-07-01 00:00:00	427.5	6127.5
Intercept Pharmaceuticals, Inc.	69516000530	2022-01-20 00:00:00	2018-07-01 00:00:00	459.56	6587.06
Intercept Pharmaceuticals, Inc.	69516000530	2022-01-20 00:00:00	2019-08-15 00:00:00	322.77	6909.83
Intercept Pharmaceuticals, Inc.	69516000530	2022-01-20 00:00:00	2020-08-20 00:00:00	338.58	7248.41
Intercept Pharmaceuticals, Inc.	69516000530	2022-01-20 00:00:00	2021-01-21 00:00:00	347.92	7596.33
Intercept Pharmaceuticals, Inc.	69516000530	2022-01-20 00:00:00	2022-01-20 00:00:00	448.18	8044.51
Intercept Pharmaceuticals, Inc.	69516001030	2022-01-20 00:00:00	2017-07-01 00:00:00	427.5	6127.5
Intercept Pharmaceuticals, Inc.	69516001030	2022-01-20 00:00:00	2018-07-01 00:00:00	459.56	6587.06
Intercept Pharmaceuticals, Inc.	69516001030	2022-01-20 00:00:00	2019-08-15 00:00:00	322.77	6909.83
Intercept Pharmaceuticals, Inc.	69516001030	2022-01-20 00:00:00	2020-08-20 00:00:00	338.58	7248.41
Intercept Pharmaceuticals, Inc.	69516001030	2022-01-20 00:00:00	2021-01-21 00:00:00	347.92	7596.33
Intercept Pharmaceuticals, Inc.	69516001030	2022-01-20 00:00:00	2022-01-20 00:00:00	448.18	8044.51
Ipsen Biopharmaceuticals, Inc.	15054004301	2022-01-01 00:00:00	2017-04-06 00:00:00	41.64	1694.04
Ipsen Biopharmaceuticals, Inc.	15054004301	2022-01-01 00:00:00	2017-06-30 00:00:00	86.96	1781
Ipsen Biopharmaceuticals, Inc.	15054004301	2022-01-01 00:00:00	2018-01-01 00:00:00	177	1958
Ipsen Biopharmaceuticals, Inc.	15054004301	2022-01-01 00:00:00	2019-01-01 00:00:00	194	2152
Ipsen Biopharmaceuticals, Inc.	15054004301	2022-01-01 00:00:00	2020-01-01 00:00:00	214	2366
Ipsen Biopharmaceuticals, Inc.	15054004301	2022-01-01 00:00:00	2021-01-12 00:00:00	106	2472
Ipsen Biopharmaceuticals, Inc.	15054004301	2022-01-01 00:00:00	2022-01-01 00:00:00	111	2583
Ipsen Biopharmaceuticals, Inc.	15054104005	2022-01-01 00:00:00	2016-03-31 00:00:00	302.9	3362.3
Ipsen Biopharmaceuticals, Inc.	15054104005	2022-01-01 00:00:00	2016-12-29 00:00:00	332.87	3695.17
Ipsen Biopharmaceuticals, Inc.	15054104005	2022-01-01 00:00:00	2018-01-01 00:00:00	365.82	4060.99
Ipsen Biopharmaceuticals, Inc.	15054104005	2022-01-01 00:00:00	2019-01-01 00:00:00	403.01	4464
Ipsen Biopharmaceuticals, Inc.	15054104005	2022-01-01 00:00:00	2020-01-01 00:00:00	442	4906
Ipsen Biopharmaceuticals, Inc.	15054104005	2022-01-01 00:00:00	2021-01-12 00:00:00	221	5127
Ipsen Biopharmaceuticals, Inc.	15054104005	2022-01-01 00:00:00	2022-01-01 00:00:00	502	5629
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2016-03-31 00:00:00	175	3744
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2016-06-30 00:00:00	74	3818
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2016-09-30 00:00:00	188	4006
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2016-12-29 00:00:00	81	4087
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2017-03-31 00:00:00	160	4247
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2017-06-30 00:00:00	85	4332
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2017-09-29 00:00:00	70	4402
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2018-01-01 00:00:00	213	4615
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2019-01-01 00:00:00	457	5072
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2020-01-01 00:00:00	503	5575
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2021-01-12 00:00:00	251	5826
Ipsen Biopharmaceuticals, Inc.	15054106003	2022-01-01 00:00:00	2022-01-01 00:00:00	262	6088
Ipsen Biopharmaceuticals, Inc.	15054106004	2022-01-01 00:00:00	2019-09-01 00:00:00	457	5072
Ipsen Biopharmaceuticals, Inc.	15054106004	2022-01-01 00:00:00	2020-01-01 00:00:00	503	5575
Ipsen Biopharmaceuticals, Inc.	15054106004	2022-01-01 00:00:00	2021-01-12 00:00:00	251	5826
Ipsen Biopharmaceuticals, Inc.	15054106004	2022-01-01 00:00:00	2022-01-01 00:00:00	262	6088
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2016-03-31 00:00:00	233	4987
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2016-06-30 00:00:00	99	5086
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2016-09-30 00:00:00	250	5336
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2016-12-29 00:00:00	107	5443
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2017-03-31 00:00:00	213	5656
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2017-06-30 00:00:00	114	5770
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2017-09-29 00:00:00	93	5863
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2018-01-01 00:00:00	284	6147
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2019-01-01 00:00:00	609	6756
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2020-01-01 00:00:00	669	7425
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2021-01-12 00:00:00	334	7759
Ipsen Biopharmaceuticals, Inc.	15054109003	2022-01-01 00:00:00	2022-01-01 00:00:00	349	8108
Ipsen Biopharmaceuticals, Inc.	15054109004	2022-01-01 00:00:00	2019-09-01 00:00:00	609	6756
Ipsen Biopharmaceuticals, Inc.	15054109004	2022-01-01 00:00:00	2020-01-01 00:00:00	669	7425
Ipsen Biopharmaceuticals, Inc.	15054109004	2022-01-01 00:00:00	2021-01-12 00:00:00	334	7759
Ipsen Biopharmaceuticals, Inc.	15054109004	2022-01-01 00:00:00	2022-01-01 00:00:00	349	8108
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2016-03-31 00:00:00	275	5884
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2016-06-30 00:00:00	116	6000
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2016-09-30 00:00:00	295	6295
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2016-12-29 00:00:00	126	6421
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2017-03-31 00:00:00	251	6672
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2017-06-30 00:00:00	134	6806
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2017-09-29 00:00:00	109	6915
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2018-01-01 00:00:00	334	7249
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2019-01-01 00:00:00	718	7967
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2020-01-01 00:00:00	789	8756
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2021-01-12 00:00:00	394	9150
Ipsen Biopharmaceuticals, Inc.	15054112003	2022-01-01 00:00:00	2022-01-01 00:00:00	412	9562
Ipsen Biopharmaceuticals, Inc.	15054112004	2022-01-01 00:00:00	2019-09-01 00:00:00	718	7967
Ipsen Biopharmaceuticals, Inc.	15054112004	2022-01-01 00:00:00	2020-01-01 00:00:00	789	8756
Ipsen Biopharmaceuticals, Inc.	15054112004	2022-01-01 00:00:00	2021-01-12 00:00:00	394	9150
Ipsen Biopharmaceuticals, Inc.	15054112004	2022-01-01 00:00:00	2022-01-01 00:00:00	412	9562