Table: q1_q4_2022_prescription_drug_wac_increases , manufacturer_name like Z*

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z  *

oshpd_id	manufacturer_name	date_reported	ndc_number	drug_product_description	wac_effective_date	wac_increase_amount	wac_after_increase	patent_expiration_date	drug_source_type	unit_sales_volume_in_us	unit_sales_volume_non_public_indicator	cost_increase_factors	cost_increase_factors_non_public_indicator	change_improvement_description	change_improvement_non_public_indicator	acquisition_date	company_acquired_from	acquisition_price	acquisition_price_non_public_indicator	acquisition_price_comment	wac_at_acquisition	wac_year_prior_to_acquisition	year_drug_introduced_to_market	wac_at_intro_to_market	supporting_documents	general_comments
Rx0000082	Zydus Pharmaceuticals (USA) Inc.	06/30/2022	68382018701	Dipyridamole 25 mg Tablets 100 ct	05/05/2022	36.09	55.94	None	Non-innovator Multiple Source Drug	None	1	None	1	None	1	None	None	None	None	None	None	None	None	None	None	This is an AB rated generic drug that was not acquired in the last 5 years. This drug was discontinued in 2015 and obsoleted from the market in 2016 based on last lot expiration date. Zydus relaunched on May 5, 2022. There were no sales of this product in the last 5 years.
Rx0000082	Zydus Pharmaceuticals (USA) Inc.	06/30/2022	68382018801	Dipyridamole 50 mg Tablets 100 ct	05/05/2022	58.14	90.11	None	Non-innovator Multiple Source Drug	None	1	None	1	None	1	None	None	None	None	None	None	None	None	None	None	This is an AB rated generic drug that was not acquired in the last 5 years. This drug was discontinued in 2015 and obsoleted from the market in 2016 based on last lot expiration date. Zydus relaunched on May 5, 2022. There were no sales of this product in the last 5 years.
Rx0000082	Zydus Pharmaceuticals (USA) Inc.	06/30/2022	68382018901	Dipyridamole 75 mg Tablets 100 ct	05/05/2022	77.79	120.57	None	Non-innovator Multiple Source Drug	None	1	None	1	None	1	None	None	None	None	None	None	None	None	None	None	This is an AB rated generic drug that was not acquired in the last 5 years. This drug was discontinued in 2015 and obsoleted from the market in 2016 based on last lot expiration date. Zydus relaunched on May 5, 2022. There were no sales of this product in the last 5 years.
Rx0000163	Zyla Life Sciences	03/31/2022	69344010101	Indomethacin Oral Suspension 25 mg per 5mL - 237mL/Bottle	02/01/2022	194.10	2154.67	None	Single Source Drug	None	1	Our pricing is guided by the value our products bring to patients and an understanding of the environment in which we operate. The following financial and nonfinancial factors, along with a narrative description and explanation of these factors, influenced our decisions to take a price action: (1) Covering Operating Expenses. In order to maintain a commercial enterprise, our revenue, at a minimum, must cover operating expenses. We consider covering operating expenses in our decision around the pricing of our products. (2) Recouping Development Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs, recoup the costs expended to develop our products. We consider covering development costs and expenses in our decision around the pricing of our products. (3) Covering and Funding Acquisition Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs and developmental costs, cover the costs expended to acquire drug products. We consider covering acquisition costs in our decision around the pricing of our products. (4) Supporting Investment in New Products. In order to maintain a commercial enterprise, we must invest money to develop and bring new products to market to help patients. We consider the costs to bring new products to market to meet unmet medical needs in our decisions around pricing our products. (5) Supporting Investment in Existing Products. In order to maintain a commercial enterprise, we must invest money to improve our existing products to bring improved products to market to help patients. We consider the costs to improve our existing products in our decisions around the pricing of our products. (6) Discounts and Rebates: We pay rebates and discounts to various stakeholders in the supply chain in connection with the sale of our products, including pharmacy benefits managers, health insurers and health plans, including government payors like California’s Medicaid program, as well as wholesalers and pharmacies. Collectively, these price concessions represent substantial dollars, and we consider them in our decisions around pricing our products. (7) Inflation: We consider the rate of annual inflation in our decisions around pricing our products.	None	None	None	01/31/2019	Iroko Pharmaceuticals, Inc	87000000	None	What Zyla US Inc. has provided in Field #17 is an estimate of a portion of the purchase price of the product acquired from Iroko. This does not include the following additional costs totaling approximately $125M: - Significant ongoing royalty payments on net sales - Additional debt burden of $55M and royalty payments associated with this debt - Cost of acquired inventory - Bankruptcy restructuring costs in connection with acquisition - Assumption of additional liabilities in connection with acquisition - Post-marketing and development costs - Commercial infrastructure costs - Intellectual Property litigation and maintenance costs - Costs to comply with regulatory requirements - Co-payment assistance program utilization costs - Significant increase in manufacturing costs	891.98	891.98	1985	232.17	None	Comment on Data element #22 and #23: Zyla utilized its access to pricing compendia (as well as solicited the assistance of a consultant) in order to provide values for these requests. Based on these searches, Zyla is unable to access WAC pricing for this product when introduced to the market. Therefore, Zyla provided the FDA Approval Date per the Orange Book for Year Drug Introduced to Market and Zyla provided the earliest WAC price readily accessible via pricing compendia portals for the NDC (in this case, 4/2/2013).
Rx0000163	Zyla Life Sciences	03/31/2022	42211010111	Indomethacin Oral Suspension 25 mg per 5mL (237mL/Bottle) Disc NDC	02/01/2022	194.10	2154.67	None	Single Source Drug	None	1	Our pricing is guided by the value our products bring to patients and an understanding of the environment in which we operate. The following financial and nonfinancial factors, along with a narrative description and explanation of these factors, influenced our decisions to take a price action: (1) Covering Operating Expenses. In order to maintain a commercial enterprise, our revenue, at a minimum, must cover operating expenses. We consider covering operating expenses in our decision around the pricing of our products. (2) Recouping Development Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs, recoup the costs expended to develop our products. We consider covering development costs and expenses in our decision around the pricing of our products. (3) Covering and Funding Acquisition Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs and developmental costs, cover the costs expended to acquire drug products. We consider covering acquisition costs in our decision around the pricing of our products. (4) Supporting Investment in New Products. In order to maintain a commercial enterprise, we must invest money to develop and bring new products to market to help patients. We consider the costs to bring new products to market to meet unmet medical needs in our decisions around pricing our products. (5) Supporting Investment in Existing Products. In order to maintain a commercial enterprise, we must invest money to improve our existing products to bring improved products to market to help patients. We consider the costs to improve our existing products in our decisions around the pricing of our products. (6) Discounts and Rebates: We pay rebates and discounts to various stakeholders in the supply chain in connection with the sale of our products, including pharmacy benefits managers, health insurers and health plans, including government payors like California’s Medicaid program, as well as wholesalers and pharmacies. Collectively, these price concessions represent substantial dollars, and we consider them in our decisions around pricing our products. (7) Inflation: We consider the rate of annual inflation in our decisions around pricing our products.	None	None	None	01/31/2019	Iroko Pharmaceuticals, Inc	87000000	None	What Zyla US Inc. has provided in Field #17 is an estimate of a portion of the purchase price of the product acquired from Iroko. This does not include the following additional costs totaling approximately $125M: - Significant ongoing royalty payments on net sales - Additional debt burden of $55M and royalty payments associated with this debt - Cost of acquired inventory - Bankruptcy restructuring costs in connection with acquisition - Assumption of additional liabilities in connection with acquisition - Post-marketing and development costs - Commercial infrastructure costs - Intellectual Property litigation and maintenance costs - Costs to comply with regulatory requirements - Co-payment assistance program utilization costs - Significant increase in manufacturing costs	891.98	891.98	1985	232.17	None	Comment on Data element #22 and #23: Zyla utilized its access to pricing compendia (as well as solicited the assistance of a consultant) in order to provide values for these requests. Based on these searches, Zyla is unable to access WAC pricing for this product when introduced to the market. Therefore, Zyla provided the FDA Approval Date per the Orange Book for Year Drug Introduced to Market and Zyla provided the earliest WAC price readily accessible via pricing compendia portals for the NDC (in this case, 4/2/2013).
Rx0000163	Zyla Life Sciences	03/31/2022	69344011311	OXAYDO (Oxycodone HCL Tablet) 5 MG 100 CT BOTTLE	02/01/2022	87.81	974.74	03/16/2025	Single Source Drug	None	1	Our pricing is guided by the value our products bring to patients and an understanding of the environment in which we operate. The following financial and nonfinancial factors, along with a narrative description and explanation of these factors, influenced our decisions to take a price action: (1) Covering Operating Expenses. In order to maintain a commercial enterprise, our revenue, at a minimum, must cover operating expenses. We consider covering operating expenses in our decision around the pricing of our products. (2) Recouping Development Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs, recoup the costs expended to develop our products. We consider covering development costs and expenses in our decision around the pricing of our products. (3) Covering and Funding Acquisition Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs and developmental costs, cover the costs expended to acquire drug products. We consider covering acquisition costs in our decision around the pricing of our products. (4) Supporting Investment in New Products. In order to maintain a commercial enterprise, we must invest money to develop and bring new products to market to help patients. We consider the costs to bring new products to market to meet unmet medical needs in our decisions around pricing our products. (5) Supporting Investment in Existing Products. In order to maintain a commercial enterprise, we must invest money to improve our existing products to bring improved products to market to help patients. We consider the costs to improve our existing products in our decisions around the pricing of our products. (6) Discounts and Rebates: We pay rebates and discounts to various stakeholders in the supply chain in connection with the sale of our products, including pharmacy benefits managers, health insurers and health plans, including government payors like California’s Medicaid program, as well as wholesalers and pharmacies. Collectively, these price concessions represent substantial dollars, and we consider them in our decisions around pricing our products. (7) Inflation: We consider the rate of annual inflation in our decisions around pricing our products.	None	None	None	None	None	None	None	None	None	None	None	None	None	This drug was not acquired in the past five years.
Rx0000163	Zyla Life Sciences	03/31/2022	69344021311	OXAYDO (Oxycodone HCL Tablet) 7.5 MG 100 CT BOTTLE	02/01/2022	131.56	1460.52	03/16/2025	Single Source Drug	None	1	Our pricing is guided by the value our products bring to patients and an understanding of the environment in which we operate. The following financial and nonfinancial factors, along with a narrative description and explanation of these factors, influenced our decisions to take a price action: (1) Covering Operating Expenses. In order to maintain a commercial enterprise, our revenue, at a minimum, must cover operating expenses. We consider covering operating expenses in our decision around the pricing of our products. (2) Recouping Development Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs, recoup the costs expended to develop our products. We consider covering development costs and expenses in our decision around the pricing of our products. (3) Covering and Funding Acquisition Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs and developmental costs, cover the costs expended to acquire drug products. We consider covering acquisition costs in our decision around the pricing of our products. (4) Supporting Investment in New Products. In order to maintain a commercial enterprise, we must invest money to develop and bring new products to market to help patients. We consider the costs to bring new products to market to meet unmet medical needs in our decisions around pricing our products. (5) Supporting Investment in Existing Products. In order to maintain a commercial enterprise, we must invest money to improve our existing products to bring improved products to market to help patients. We consider the costs to improve our existing products in our decisions around the pricing of our products. (6) Discounts and Rebates: We pay rebates and discounts to various stakeholders in the supply chain in connection with the sale of our products, including pharmacy benefits managers, health insurers and health plans, including government payors like California’s Medicaid program, as well as wholesalers and pharmacies. Collectively, these price concessions represent substantial dollars, and we consider them in our decisions around pricing our products. (7) Inflation: We consider the rate of annual inflation in our decisions around pricing our products.	None	None	None	None	None	None	None	None	None	None	None	None	None	This drug was not acquired in the past five years.
Rx0000163	Zyla Life Sciences	03/31/2022	69344014443	Sprix 15.75mg/1 Spray, Metered (5 Bottles per Carton)	02/01/2022	144.97	2245.94	None	Innovator Multiple Source Drug	None	1	Our pricing is guided by the value our products bring to patients and an understanding of the environment in which we operate. The following financial and nonfinancial factors, along with a narrative description and explanation of these factors, influenced our decisions to take a price action: (1) Covering Operating Expenses. In order to maintain a commercial enterprise, our revenue, at a minimum, must cover operating expenses. We consider covering operating expenses in our decision around the pricing of our products. (2) Recouping Development Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs, recoup the costs expended to develop our products. We consider covering development costs and expenses in our decision around the pricing of our products. (3) Covering and Funding Acquisition Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs and developmental costs, cover the costs expended to acquire drug products. We consider covering acquisition costs in our decision around the pricing of our products. (4) Supporting Investment in New Products. In order to maintain a commercial enterprise, we must invest money to develop and bring new products to market to help patients. We consider the costs to bring new products to market to meet unmet medical needs in our decisions around pricing our products. (5) Supporting Investment in Existing Products. In order to maintain a commercial enterprise, we must invest money to improve our existing products to bring improved products to market to help patients. We consider the costs to improve our existing products in our decisions around the pricing of our products. (6) Discounts and Rebates: We pay rebates and discounts to various stakeholders in the supply chain in connection with the sale of our products, including pharmacy benefits managers, health insurers and health plans, including government payors like California’s Medicaid program, as well as wholesalers and pharmacies. Collectively, these price concessions represent substantial dollars, and we consider them in our decisions around pricing our products. (7) Inflation: We consider the rate of annual inflation in our decisions around pricing our products.	None	None	None	None	None	None	None	None	None	None	None	None	None	This drug was not acquired in the past five years.
Rx0000163	Zyla Life Sciences	03/31/2022	69344020429	Zorvolex 35 MG Capsule 90 EA	02/01/2022	70.72	785.07	04/23/2030	Single Source Drug	None	1	Our pricing is guided by the value our products bring to patients and an understanding of the environment in which we operate. The following financial and nonfinancial factors, along with a narrative description and explanation of these factors, influenced our decisions to take a price action: (1) Covering Operating Expenses. In order to maintain a commercial enterprise, our revenue, at a minimum, must cover operating expenses. We consider covering operating expenses in our decision around the pricing of our products. (2) Recouping Development Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs, recoup the costs expended to develop our products. We consider covering development costs and expenses in our decision around the pricing of our products. (3) Covering and Funding Acquisition Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs and developmental costs, cover the costs expended to acquire drug products. We consider covering acquisition costs in our decision around the pricing of our products. (4) Supporting Investment in New Products. In order to maintain a commercial enterprise, we must invest money to develop and bring new products to market to help patients. We consider the costs to bring new products to market to meet unmet medical needs in our decisions around pricing our products. (5) Supporting Investment in Existing Products. In order to maintain a commercial enterprise, we must invest money to improve our existing products to bring improved products to market to help patients. We consider the costs to improve our existing products in our decisions around the pricing of our products. (6) Discounts and Rebates: We pay rebates and discounts to various stakeholders in the supply chain in connection with the sale of our products, including pharmacy benefits managers, health insurers and health plans, including government payors like California’s Medicaid program, as well as wholesalers and pharmacies. Collectively, these price concessions represent substantial dollars, and we consider them in our decisions around pricing our products. (7) Inflation: We consider the rate of annual inflation in our decisions around pricing our products.	None	None	None	01/31/2019	Iroko Pharmaceuticals, Inc	87000000	None	What Zyla US Inc. has provided in Field #17 is an estimate of a portion of the purchase price of the product acquired from Iroko. This does not include the following additional costs totaling approximately $125M: - Significant ongoing royalty payments on net sales - Additional debt burden of $55M and royalty payments associated with this debt - Cost of acquired inventory - Bankruptcy restructuring costs in connection with acquisition - Assumption of additional liabilities in connection with acquisition - Post-marketing and development costs - Commercial infrastructure costs - Intellectual Property litigation and maintenance costs - Costs to comply with regulatory requirements - Co-payment assistance program utilization costs - Significant increase in manufacturing costs	383.05	350.14	2013	225.00	None	Comment on Data element #22 and #23: Zyla utilized its access to pricing compendia (as well as solicited the assistance of a consultant) in order to provide values for these requests. Based on these searches, Zyla is unable to access WAC pricing for this product when introduced to the market. Therefore, Zyla provided the FDA Approval Date per the Orange Book for Year Drug Introduced to Market and Zyla provided the earliest WAC price readily accessible via pricing compendia portals for the NDC (in this case, 10/28/2013).
Rx0000163	Zyla Life Sciences	03/31/2022	42211020429	Zorvolex 35 MG Capsule 90 EA - Disc NDC	02/01/2022	70.72	785.07	04/23/2030	Single Source Drug	None	1	Our pricing is guided by the value our products bring to patients and an understanding of the environment in which we operate. The following financial and nonfinancial factors, along with a narrative description and explanation of these factors, influenced our decisions to take a price action: (1) Covering Operating Expenses. In order to maintain a commercial enterprise, our revenue, at a minimum, must cover operating expenses. We consider covering operating expenses in our decision around the pricing of our products. (2) Recouping Development Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs, recoup the costs expended to develop our products. We consider covering development costs and expenses in our decision around the pricing of our products. (3) Covering and Funding Acquisition Costs. In order to maintain a commercial enterprise, our revenue, must, in addition to covering operating costs and developmental costs, cover the costs expended to acquire drug products. We consider covering acquisition costs in our decision around the pricing of our products. (4) Supporting Investment in New Products. In order to maintain a commercial enterprise, we must invest money to develop and bring new products to market to help patients. We consider the costs to bring new products to market to meet unmet medical needs in our decisions around pricing our products. (5) Supporting Investment in Existing Products. In order to maintain a commercial enterprise, we must invest money to improve our existing products to bring improved products to market to help patients. We consider the costs to improve our existing products in our decisions around the pricing of our products. (6) Discounts and Rebates: We pay rebates and discounts to various stakeholders in the supply chain in connection with the sale of our products, including pharmacy benefits managers, health insurers and health plans, including government payors like California’s Medicaid program, as well as wholesalers and pharmacies. Collectively, these price concessions represent substantial dollars, and we consider them in our decisions around pricing our products. (7) Inflation: We consider the rate of annual inflation in our decisions around pricing our products.	None	None	None	01/31/2019	Iroko Pharmaceuticals, Inc	87000000	None	What Zyla US Inc. has provided in Field #17 is an estimate of a portion of the purchase price of the product acquired from Iroko. This does not include the following additional costs totaling approximately $125M: - Significant ongoing royalty payments on net sales - Additional debt burden of $55M and royalty payments associated with this debt - Cost of acquired inventory - Bankruptcy restructuring costs in connection with acquisition - Assumption of additional liabilities in connection with acquisition - Post-marketing and development costs - Commercial infrastructure costs - Intellectual Property litigation and maintenance costs - Costs to comply with regulatory requirements - Co-payment assistance program utilization costs - Significant increase in manufacturing costs	383.05	350.14	2013	225.00	None	Comment on Data element #22 and #23: Zyla utilized its access to pricing compendia (as well as solicited the assistance of a consultant) in order to provide values for these requests. Based on these searches, Zyla is unable to access WAC pricing for this product when introduced to the market. Therefore, Zyla provided the FDA Approval Date per the Orange Book for Year Drug Introduced to Market and Zyla provided the earliest WAC price readily accessible via pricing compendia portals for the NDC (in this case, 10/28/2013).