Table: q1_q4_2022_prescription_drug_wac_increases , manufacturer_name like L*

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oshpd_id manufacturer_name date_reported ndc_number drug_product_description wac_effective_date wac_increase_amount wac_after_increase patent_expiration_date drug_source_type unit_sales_volume_in_us unit_sales_volume_non_public_indicator cost_increase_factors cost_increase_factors_non_public_indicator change_improvement_description change_improvement_non_public_indicator acquisition_date company_acquired_from acquisition_price acquisition_price_non_public_indicator acquisition_price_comment wac_at_acquisition wac_year_prior_to_acquisition year_drug_introduced_to_market wac_at_intro_to_market supporting_documents general_comments
Rx0000083 Laboratoire HRA Pharma 03/31/2022 76336008060 Lysodren 500 mg tablets 100 count bottles 03/01/2022 152.01 1165.40 None Single Source Drug None 1 None 1 None 1 03/15/2018 BMS None 1 Trade secret of privately held company. This information is privy only to a few select executives. 479.95 479.95 1970 99.95 None Column 22 is a best estimate. Pricing software does not report that far back to my knowledge.
Rx0000083 Laboratoire HRA Pharma 03/31/2022 76336045518 Metopirone 250 mg capsules 18 count bottles 03/01/2022 144.93 724.65 None Single Source Drug None 1 None 1 None 1 03/01/2011 Novartis None 1 Trade secret of privately held company. Only a select few executives know the purchase price for this drug. 289.15 289.15 1961 99.95 None Column 22 is a best estimate. Pricing software does not report that far back to my knowledge.
Rx0000009 Lantheus Medical Imaging, Inc. 03/31/2022 11994001116 DEFINITY US 16Vial KIT. INJECTION, SUSPENSION, 6.52 mg/mL. 16 VIAL, GLASS in 1 CARTON (11994-011-16) > 1.5 mL in 1 VIAL, GLASS 01/01/2022 270.30 4775.36 05/04/2037 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000009 Lantheus Medical Imaging, Inc. 03/31/2022 11994001104 DEFINITY US 4Vial KIT. INJECTION, SUSPENSION, 6.52 mg/mL. 4 VIAL, GLASS in 1 CARTON (11994-011-04) > 1.5 mL in 1 VIAL, GLASS 01/01/2022 90.10 1216.37 05/04/2037 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000413 Leadiant Biosciences, Inc. 03/31/2022 54482005401 Matulane (Procarbazine Hydrochloride) 50mg Capsules (100 p/bottle) 01/01/2022 1561.19 11969.11 None Single Source Drug None 1 Our pricing has been adjusted substantially in consideration of increased manufacturing and supply costs, increased regulatory maintenance costs, and decreasing volumes that make it incrementally onerous for Leadiant to keep Matulane in the market and available to patients. None Not Applicable None None None None None None None None None None None We take decisions related to the pricing of our medicines very seriously. Given the complexities of manufacturing products for extremely small patient populations, and the difficulties of maintaining their availability to patients over time, Leadiant strives to find the right balance between ensuring that patients have access to the medicines they need while investing in new therapies for new groups of underserved populations. The costs to produce rare disease products typically increases over time, unlike most other industries. At the same time, our research and development costs are offset by revenues from our approved products.
Rx0000025 Lundbeck LLC 03/31/2022 67386082019 Northera 100mg. 90 Capsules 01/03/2022 153.26 3218.39 None Single Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 09/30/2022 67386082019 Northera 100mg. 90 Capsules 07/01/2022 144.83 3363.22 02/18/2021 Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386082119 Northera 200mg. 90 Capsules 01/03/2022 306.51 6436.76 None Single Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 09/30/2022 67386082119 Northera 200mg. 90 Capsules 07/01/2022 289.65 6726.41 02/18/2021 Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386082219 Northera 300mg. 90 Capsules 01/03/2022 459.77 9655.16 None Single Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 09/30/2022 67386082219 Northera 300mg. 90 Capsules 07/01/2022 434.48 10089.64 02/18/2021 Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386031401 Onfi 10mg. 100 Tablets 01/03/2022 120.61 2532.74 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386031501 Onfi 20mg. 100 Tablets 01/03/2022 241.21 5065.42 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386031321 Onfi Oral Suspension 2.5mg/mL 120mL Bottle 01/03/2022 63.37 1330.72 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386011101 Sabril 500mg. 100 Tablets 01/03/2022 1051.19 18571.01 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 09/30/2022 67386011101 Sabril 500mg. 100 Tablets 07/01/2022 649.99 19221.00 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386021165 Sabril 500mg. 50 Packets 500mg. each 01/03/2022 525.60 9285.52 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 09/30/2022 67386021165 Sabril 500mg. 50 Packets 500mg. each 07/01/2022 324.99 9610.51 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386042101 Xenazine 12.5mg. 112 Tablets 01/03/2022 845.27 17750.67 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 09/30/2022 67386042101 Xenazine 12.5mg. 112 Tablets 07/01/2022 798.78 18549.45 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 03/31/2022 67386042201 Xenazine 25.0mg. 112 Tablets 01/03/2022 1690.54 35501.35 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.
Rx0000025 Lundbeck LLC 09/30/2022 67386042201 Xenazine 25.0mg. 112 Tablets 07/01/2022 1597.56 37098.91 None Innovator Multiple Source Drug None 1 "Brain health is Lundbeck’s sole focus and there is a high cost and high risk to developing and bringing therapies for brain diseases to market. As we price our therapies, we carefully balance the high-risk nature of this work with the needs of patients who depend on us to continue seeking new ways to improve their quality of life. Our pricing practices reflect these realities and focus on the value that our treatments bring to patients and society, the need to invest in continued innovation, and our commitment to affordability – offering patient assistance programs that can help ensure patients who rely on our medicines have access to our therapies." None None 1 None None None None None None None None None None Acquisition fields not completed as product was not acquired in the last 5 years.