Table: q1_q4_2021_prescription_drug_wac_increases_5_year_history , manufacturer_name like R*

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manufacturer_name	ndc_number	effective_date	history_effective_date	wac_increase_amount	wac_amount
Radius Health, Inc.	70539000101	2021-01-01 00:00:00	2018-02-22 00:00:00	51.18	1720.88
Radius Health, Inc.	70539000101	2021-01-01 00:00:00	2019-01-01 00:00:00	101.53	1822.41
Radius Health, Inc.	70539000101	2021-01-01 00:00:00	2020-01-01 00:00:00	143.97	1966.38
Radius Health, Inc.	70539000101	2021-01-01 00:00:00	2021-01-01 00:00:00	155.34	2121.72
Radius Health, Inc.	70539000102	2021-01-01 00:00:00	2018-02-22 00:00:00	51.18	1720.88
Radius Health, Inc.	70539000102	2021-01-01 00:00:00	2019-01-01 00:00:00	101.53	1822.41
Radius Health, Inc.	70539000102	2021-01-01 00:00:00	2020-01-01 00:00:00	143.97	1966.38
Radius Health, Inc.	70539000102	2021-01-01 00:00:00	2021-01-01 00:00:00	155.34	2121.72
Recordati Rare Diseases, inc.	52292012252	2021-01-06 00:00:00	2016-07-01 00:00:00	144.64	1667.14
Recordati Rare Diseases, inc.	52292012252	2021-01-06 00:00:00	2017-06-01 00:00:00	165.05	1832.19
Recordati Rare Diseases, inc.	52292012252	2021-01-06 00:00:00	2018-04-02 00:00:00	183.22	2015.41
Recordati Rare Diseases, inc.	52292012252	2021-01-06 00:00:00	2020-01-06 00:00:00	423.24	2438.65
Recordati Rare Diseases, inc.	52292012252	2021-01-06 00:00:00	2021-01-06 00:00:00	243.87	2682.52
Recordati Rare Diseases, inc.	55292010401	2021-01-06 00:00:00	2017-05-22 00:00:00	405.04	1125.1
Recordati Rare Diseases, inc.	55292010401	2021-01-06 00:00:00	2018-01-03 00:00:00	281.28	1406.38
Recordati Rare Diseases, inc.	55292010401	2021-01-06 00:00:00	2019-01-07 00:00:00	140.64	1547.02
Recordati Rare Diseases, inc.	55292010401	2021-01-06 00:00:00	2020-01-06 00:00:00	154.7	1701.72
Recordati Rare Diseases, inc.	55292010401	2021-01-06 00:00:00	2021-01-06 00:00:00	170.17	1871.89
Recordati Rare Diseases, inc.	55292020111	2021-01-06 00:00:00	2017-01-04 00:00:00	70.84	1487.54
Recordati Rare Diseases, inc.	55292020111	2021-01-06 00:00:00	2018-01-03 00:00:00	148.75	1636.29
Recordati Rare Diseases, inc.	55292020111	2021-01-06 00:00:00	2019-01-07 00:00:00	130.74	1767.03
Recordati Rare Diseases, inc.	55292020111	2021-01-06 00:00:00	2020-01-06 00:00:00	141.36	1908.39
Recordati Rare Diseases, inc.	55292020111	2021-01-06 00:00:00	2021-01-06 00:00:00	152.67	2061.06
Recordati Rare Diseases, inc.	55292030401	2021-01-06 00:00:00	2018-01-03 00:00:00	196.02	980.1
Recordati Rare Diseases, inc.	55292030401	2021-01-06 00:00:00	2019-01-07 00:00:00	98.03	1078.13
Recordati Rare Diseases, inc.	55292030401	2021-01-06 00:00:00	2020-01-06 00:00:00	107.85	1185.98
Recordati Rare Diseases, inc.	55292030401	2021-01-06 00:00:00	2021-01-06 00:00:00	118.6	1304.58
Recordati Rare Diseases, inc.	55292081155	2021-01-06 00:00:00	2016-01-06 00:00:00	111.7	1228.7
Recordati Rare Diseases, inc.	55292081155	2021-01-06 00:00:00	2017-01-04 00:00:00	122.87	1351.57
Recordati Rare Diseases, inc.	55292081155	2021-01-06 00:00:00	2017-11-27 00:00:00	337.89	1689.46
Recordati Rare Diseases, inc.	55292081155	2021-01-06 00:00:00	2019-01-07 00:00:00	168.95	1858.41
Recordati Rare Diseases, inc.	55292081155	2021-01-06 00:00:00	2020-01-06 00:00:00	185.84	2044.25
Recordati Rare Diseases, inc.	55292081155	2021-01-06 00:00:00	2021-01-06 00:00:00	204.43	2248.68
Redhill Biopharma, Inc.	71068000110	2021-01-01 00:00:00	2019-11-12 00:00:00	13.0	157.0
Redhill Biopharma, Inc.	71068000110	2021-01-01 00:00:00	2020-01-01 00:00:00	14.24	171.24
Redhill Biopharma, Inc.	71068000110	2021-01-01 00:00:00	2021-01-01 00:00:00	5.13	176.37
Rigel Pharmaceuticals, Inc.	71332000101	2021-06-29 00:00:00	2019-01-23 00:00:00	378.0	9828.0
Rigel Pharmaceuticals, Inc.	71332000101	2021-06-29 00:00:00	2019-07-19 00:00:00	484.0	10762.0
Rigel Pharmaceuticals, Inc.	71332000101	2021-06-29 00:00:00	2020-02-15 00:00:00	484.0	11246.0
Rigel Pharmaceuticals, Inc.	71332000101	2021-06-29 00:00:00	2020-07-07 00:00:00	564.0	11810.0
Rigel Pharmaceuticals, Inc.	71332000101	2021-06-29 00:00:00	2021-06-29 00:00:00	590.0	12400.0
Rigel Pharmaceuticals, Inc.	71332000201	2021-06-29 00:00:00	2019-01-23 00:00:00	378.0	9828.0
Rigel Pharmaceuticals, Inc.	71332000201	2021-06-29 00:00:00	2019-07-19 00:00:00	934.0	10762.0
Rigel Pharmaceuticals, Inc.	71332000201	2021-06-29 00:00:00	2020-02-15 00:00:00	484.0	11246.0
Rigel Pharmaceuticals, Inc.	71332000201	2021-06-29 00:00:00	2020-07-07 00:00:00	564.0	11810.0
Rigel Pharmaceuticals, Inc.	71332000201	2021-06-29 00:00:00	2021-06-29 00:00:00	590.0	12400.0