Table: q1_q4_2023_prescription_drug_wac_increases , manufacturer_name like K*

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oshpd_id manufacturer_name date_reported ndc_number drug_product_description drug_category drug_category_source wac_effective_date wac_increase_amount wac_after_increase patent_expiration_date drug_source_type unit_sales_volume_in_us unit_sales_volume_non_public_indicator cost_increase_factors cost_increase_factors_non_public_indicator change_improvement_description change_improvement_non_public_indicator acquisition_date company_acquired_from acquisition_price acquisition_price_non_public_indicator acquisition_price_comment wac_at_acquisition wac_year_prior_to_acquisition year_drug_introduced_to_market wac_at_intro_to_market supporting_documents general_comments
Rx0000127 Karyopharm Therapeutics Inc. 09/30/2023 72237010305 Xpovio (100 MG Once Weekly) Oral Tablet Therapy Pack 50 MG, 2 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 07/01/2023 1048.00 27907.00 None Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 09/30/2023 72237010207 Xpovio (40 MG Once Weekly) Oral Tablet Therapy Pack 40 MG, 1 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 07/01/2023 1048.00 27907.00 None Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 09/30/2023 72237010206 Xpovio (40 MG Twice Weekly) Oral Tablet Therapy Pack 40 MG, 2 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 07/01/2023 1048.00 27907.00 None Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 09/30/2023 72237010401 Xpovio (60 MG Once Weekly) Oral Tablet Therapy Pack 60 MG, 1 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 07/01/2023 1048.00 27907.00 None Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 09/30/2023 72237010103 Xpovio (60 MG Twice Weekly) Oral Tablet Therapy Pack 20 MG, 6 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 07/01/2023 1048.00 27907.00 None Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 09/30/2023 72237010202 Xpovio (80 MG Once Weekly) Oral Tablet Therapy Pack 40 MG, 2 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 07/01/2023 1048.00 27907.00 None Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 09/30/2023 72237010104 Xpovio (80 MG Twice Weekly) Oral Tablet Therapy Pack 20 MG, 8 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 07/01/2023 1048.00 27907.00 None Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 03/31/2023 72237010103 Xpovio, Selinexor Tab Therapy Pack 20 MG (60 MG Twice Weekly), 6 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 01/01/2023 1497.00 26859.00 08/14/2035 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 03/31/2023 72237010104 Xpovio, Selinexor Tab Therapy Pack 20 MG (80 MG Twice Weekly), 8 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 01/01/2023 1497.00 26859.00 08/14/2035 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 03/31/2023 72237010207 Xpovio, Selinexor Tab Therapy Pack 40 MG (40 MG Once Weekly), 1 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 01/01/2023 1497.00 26859.00 08/14/2035 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 03/31/2023 72237010206 Xpovio, Selinexor Tab Therapy Pack 40 MG (40 MG Twice Weekly), 2 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 01/01/2023 1497.00 26859.00 08/14/2035 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 03/31/2023 72237010305 Xpovio, Selinexor Tab Therapy Pack 50 MG (100 MG Once Weekly), 2 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 01/01/2023 1497.00 26859.00 08/14/2035 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 03/31/2023 72237010401 Xpovio, Selinexor Tab Therapy Pack 60 MG (60 MG Once Weekly), 1 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 01/01/2023 1497.00 26859.00 08/14/2035 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000127 Karyopharm Therapeutics Inc. 03/31/2023 72237010202 Xpovio,Selinexor Tab Therapy Pack 40 MG (80 MG Once Weekly), 2 Each, Unit-of-Use, Disp Pack Qty 4 Brand FDA 01/01/2023 1497.00 26859.00 08/14/2035 Single Source Drug None 1 None 1 None 1 None None None None None None None None None None None
Rx0000264 Kedrion Biopharma Inc. 03/31/2023 76125090020 Gammaked 200ml 1 vial in package Brand FDA 01/16/2023 265.40 3756.20 12/31/2023 Single Source Drug 84129 None rising cost of plasma and manufacturing None na None None None None None None None None None None None None
Rx0000264 Kedrion Biopharma Inc. 03/31/2023 76125090010 Gammaked 100ml 1 vial in package Brand FDA 01/16/2023 132.70 1878.10 12/31/2023 Single Source Drug 66461 None rising cost of plasma and manufacturing None na None None None None None None None None None None None None
Rx0000264 Kedrion Biopharma Inc. 03/31/2023 76125090050 Gammaked 50ml 1 vial in package Brand FDA 01/16/2023 66.35 939.05 12/31/2023 Single Source Drug 29199 None rising cost of plasma and manufacturing None na None None None None None None None None None None None None
Rx0000386 KVK Tech, Inc. 06/30/2023 10702006601 DEXTROAMPHETAMINE SULFATE TABLET 10 MG 100 Generic FDA 06/02/2023 44.00 96.00 None Non-innovator Multiple Source Drug 5828800 None Market conditions and dynamics None n/a None None None None None None None None None None None Drug was not acquired within the last 5 years
Rx0000386 KVK Tech, Inc. 06/30/2023 10702007101 OXYMORPHONE HCL TABLET 10 MG 100 Generic FDA 06/02/2023 78.00 248.00 None Non-innovator Multiple Source Drug 323100 None Market conditions and dynamics None n/a None None None None None None None None None None None Drug was not acquired within the last 5 years
Rx0000060 Kyowa Kirin, Inc. 09/30/2023 69794010201 CRYSVITA® (burosumab-twza) injection, for subcutaneous use, 10 mg/mL, 1 ML, single dose vial Brand FDA 07/03/2023 123.48 4239.48 None Single Source Drug None 1 None 1 A change or improvement in the product does not necessitate the price increase. None None None None None None None None None None None None
Rx0000060 Kyowa Kirin, Inc. 09/30/2023 69794020301 CRYSVITA® (burosumab-twza) injection, for subcutaneous use, 20 mg/mL, 1 ML, single dose vial Brand FDA 07/03/2023 246.96 8478.96 None Single Source Drug None 1 None 1 A change or improvement in the product does not necessitate the price increase. None None None None None None None None None None None None
Rx0000060 Kyowa Kirin, Inc. 09/30/2023 69794030401 CRYSVITA® (burosumab-twza) injection, for subcutaneous use, 30 mg/mL, 1 ML, single dose vial Brand FDA 07/03/2023 370.44 12718.44 None Single Source Drug None 1 None 1 A change or improvement in the product does not necessitate the price increase. None None None None None None None None None None None None
Rx0000060 Kyowa Kirin, Inc. 03/31/2023 42747060290 Nourianz Oral Tablet 20 MG, 90 Each, Bottle Brand FDA 01/03/2023 257.51 5407.76 09/05/2027 Single Source Drug None 1 None 1 N/A None None None None None None None None None None None None
Rx0000060 Kyowa Kirin, Inc. 03/31/2023 42747060490 Nourianz Oral Tablet 40 MG, 90 Each, Bottle Brand FDA 01/03/2023 257.51 5407.76 09/05/2027 Single Source Drug None 1 None 1 N/A None None None None None None None None None None None None